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Product name Hesperidin Methyl Chalcone
Source Bitter Orange, Citrus Aurantium Derivatives, Citrus ExtractDerivatives, Hesperidin Derivatives
Appearance Yellow to orange crystalline powder 
Specification Hesperidin Methyl Chalcone 98% UV 
Synonyms HMC, Methyl Hesperidina Chalcone, Hesperidina Methyl Chalcone
CAS Number 24292-52-2
Molecular Weight 624.59
Molecular Formula C29H36O15
Storage Store at room temperature
Package 25kg/drum
benefits support vascular integrity,anti-aging as oxidants used in supplement and cosmetics

What is Hesperidin Methyl Chalcone?

Hesperidin methyl chalcone is found in naturally high concentrations in the peel, pulp, and membranes of citrus fruit, such as grapefruits, lemons, and oranges. Hesperidin methyl chalcone has antioxidant properties, which help it to combat the inflammation and cell damage caused by free radicals.X7sShanghai Natural Bio-engineering Co., Ltd

Most people get some hesperidin and other bioflavonoids naturally through diet. People who are deficient in hesperidin can experience abnormal capillary leakiness, leg aches and leg swelling. Hesperidin and derivatives like hesperidin methyl chalcone strengthen and protect capillaries and small veins so they are less likely to leak fluid into the surrounding tissue. 

Hesperidin Methyl Chalcone VS Hesperidin

Hesperidin methyl chalcone is a compound derived from hesperidin. Hesperidin is an antioxidant bioflavonoid found in large quantities in citrus fruits. Hesperidin Methyl Chalcone, according to Wikipedia, is the methylated form of hesperidin, a flavonoid nutrient derived from citrus fruits that helps support vascular integrity and protects heart and blood vessels. Hesperidin in its original form is not very water soluble, but hesperidin methyl chalcone (HMC) is highly water soluble for greater absorption! A great antioxidant.

Benefits of Hesperidin Methyl Chalcone

Hesperidin Methyl Chalcone is so popular that it has been widely used in both dietary supplement industry as well as cosmetics industry. The key benefits include anti-aging benefits, support vascular integrity and protects heart and blood vessels, etc.

Hesperidin Methyl Chalcone and vascular integrity support

One study showed that hesperidin methyl chalcone in combination with other ingredients reduced leg tightness and swelling in people with chronic venous insufficiency and varicose veins. There is also some evidence that taking hesperidin methyl chalcone as a dietary supplement reduces hot flashes in women going through menopause. Cosmetic manufacturers add hesperidin methyl chalcone to products formulated to reduce dark circles under the eyes, based on the idea that it strengthens the walls of blood vessels. 
In skin care products, hesperidin methyl chalcone improves the appearance of the characteristic, bluish-black circles that can form under the eyes. The skin under the eyes is much thinner than on other parts of the face and body. As a result, dark bluish-black circles can form under the eyes, giving a tired and prematurely aged appearance. These discolored areas are the result of blood flowing through the capillaries that lie just under the surface of the thin, fragile skin, which is almost translucent. Hesperidin methyl chalcone strengthens the capillary walls and lowers the blood flow passing through the tiny blood vessels. It also prevents blood leaking out of the capillaries by reducing the permeability of the blood vessel walls. With stronger capillary walls and less visible blood flow, the skin loses its bluish-black hue.

Hesperidin Methyl Chalcone as antioxidant

Because hesperidin methyl chalcone has antioxidant activity, it is also an ingredient formulated in some anti-aging products including anti-aging night creams, moisturizers, sunscreens and body lotions. Antioxidants help to protect skin cells against free radicals produced by exposure to sunlight and pollutants in the environment. Most research showing benefits of hesperidin methyl chalcone have used oral supplements. Less research has focused on its effects topically. 

Hesperidin Methyl Chalcone in cosmetics

Dark circles under the eye area are often associated with aging. Although dark circles can appear at any age, they often become more pronounced as an individual matures. The reason for this is that the skin becomes thinner and more fragile with age, as collagen and elastin levels fall. Because of its ability to reduce dark circles under the eyes, hesperidin methyl chalcone can be found listed as an ingredient in some anti-aging eye creams and serums.
Hesperidin methyl chalcone is also listed as an ingredient in a number of facial creams and lotions that tackle skin redness. Skin redness can be a symptom of a skin condition, such as rosacea, or simply the result of skin hypersensitivity. Hesperidin methyl chalcone works to improve skin tone and reduce redness by calming inflammation and decreasing capillary permeability, which can cause high coloration of the skin.

Hesperidin Methyl Chalcone as a supplement ingredient

When hesperidin methyl chalcone is taken as an oral supplement, it boosts the integrity of blood vessels and improves blood flow. As a result, hesperidin methyl chalcone provides relief for individuals experiencing fibroid tumors and endometriosis. Hesperidin methyl chalcone can also be found as an ingredient in vitamin complexes that are designed to help menopausal women. Hesperidin methyl chalcone helps to alleviate the hot flashes that are one of the most common symptoms experienced by menopausal women. It does this by stabilizing vasomotor activity and improving capillary strength, which regulates blood flow and reduces fluctuations in body temperature.
Oral supplements of hesperidin methyl chalcone have been scientifically-proven to improve venous insufficiency, making them an effective treatment for varicose veins, circulatory conditions related to diabetes, and hemorrhoids. In supplements that are produced to address circulatory conditions, hesperidin methyl chalcone is often combined with another bioflavinoid known as diosmin. These two bioflavinoids are more potent when taken together.

Side effects of Hesperidin Methyl Chalcone

Hesperidin methyl chalcone appears to be safe when used as a dietary supplement. As a topical agent, it hasn’t been evaluated for safety by an industry panel, although there are no reports of contact dermatitis or allergic reactions in the literature. However, people with sensitive skin may experience some tingling and redness when they use it. 

Where to buy Hesperidin Methyl Chalcone?

Shanghai Natural Bio-engineering Co., Ltd is the export branch of Hunan Keyuan Bio-products  Co., Ltd. Hesperidin Methyl Chalcone, hesperidin, diosmin and lutin are our key products, and  regular bulk stock is available all year around,if you are in need,pleas kindly let us know. we can produce as per the client`s requirement including microbiology.

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