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Product name Finasteride
Synonyms proscar, propecia, N-(1,1-dimethylethyl)-3-oxo-(5α,17β)-4-azaandrost-1-ene-17-carboxamide
CAS Registry Number 98319-26-7
Specification 99%
Apperance white or off-white crystalline powder
Molecular Formula C23H36N2O2
Molecular Weight 372.55
dosage 5 mg orally once a day
Main benefits treat male pattern hair loss, benign prostatic hyperplasia (BPH)
Applied industries Pharmaceuticals,medicines,drugs,APIs, Intermediates

 What is finasteride?

Finasteride, according to Wikipedia, is a synthetic drug for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). There are some well-known brand names such as Proscar and Propecia, some other generic names include N-(1,1-dimethylethyl)-3-oxo-(5α,17β)-4-azaandrost-1-ene-17-carboxamide,etc.

How finasteride works(MECHANISM of action)

Finasteride blocks the action of an enzyme called 5-alpha-reductase. This enzyme changes testosterone to another hormone that causes the prostate to grow or hair loss in males. It will increase testosterone levels in the body, which decreases prostate size and increases hair growth on the scalp. The effect of finasteride on the prostate and scalp will only last as long as the medicine is taken. When it is stopped, the prostate begins to grow again and the hair will be lost.
 
The prostate gland is located around the tube which empties urine from the bladder (urethra). As the prostate gland enlarges, usually after 50 years of age, it can obstruct or partially block the urine flow. This leads to symptoms which include dribbling of urine, narrow stream, problems starting urine flow, interruption while urinating, and a feeling of incomplete emptying. Other symptoms include wetting and staining of clothes, urinary burning, and urgency.
 
Prostate gland enlargement (benign prostatic hyperplasia or BPH), is directly dependent on DHT (a hormone converted from the male hormone testosterone). Finasteride inhibits the enzyme necessary for the conversion of testosterone to DHT in the prostate. Therefore, administration of finasteride lowers blood and tissue DHT levels and helps reduce the size of the prostate gland. 
Although reductions in the size of the prostate gland can occur in virtually all the patients who take finasteride, only 50% will experience improvement in the symptoms of BPH. Patients generally respond to finasteride in several weeks, but it often takes 6 months for the patient to receive the full effect of the drug.

Benefits of taking finasteride medicines

Male Pattern Baldness Treatment

Finasteride is licensed for the treatment of certain types of male pattern baldness in men, including hair loss at the very top of the head and hair loss near the front and center of the head. Finasteride has not been shown to be effective for hair loss near the temples. Even though male pattern baldness can be a cause of female hair loss (called female pattern baldness), finasteride has not been shown to be effective for women.
 

Enlarged Prostate Treatment

An enlarged prostate (known medically as benign prostatic hyperplasia, benign prostatic hypertrophy, or BPH is very common among older men. The prostate begins growing during puberty and continues to grow throughout most of adulthood. Usually, this is not a problem until men reach their fifties or sixties. When the prostate becomes too large, it can press against the urethra, causing problems with urination. Specific BPH symptoms may include frequent urination (which is especially noticeable at night), difficulty fully emptying the bladder when urinating, and other problems.
 
Treatment for BPH includes watchful waiting (doing nothing, especially if symptoms are not bothersome), medication, and surgery. Finasteride is one of the medications for BPH.
Side effects of taking finasteride medicines
 
Along with its needed effects, finasteride may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking finasteride: Chills, cold sweats, confusion,dizziness, faintness, or lightheadedness when getting up from a lying or sitting position,etc.

Dosage of finasteride

The recommended dose of Finasteride is 5 mg taken once a day in combination with the alpha-blocker doxazosin. Patients should be evaluated for efficacy after 6 to 12 months. If after this time there is no improvement, finasteride should be discontinued. Doses greater than 5 mg/day do not result in increased dihydrotestosterone suppression and should not be used.

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